Daimon Michiko (Yonekura) is a 37-year-old freelance surgeon who is part of a questionable ?doctor placement service? that has her wander from hospital to hospital. The harsh environment at the hospitals led many doctors to retire from their positions, forcing hospitals to make use of said program to fill the empty spots at least temporary. However, Michiko doesn?t look like a doctor at all with her flashy clothes and eccentric attitude. In the first episode she raises objections to a certain operation which is planned to be done by the head of a hospital who hasn?t performed an operation for a very long time. This causes Michiko to incur odium at the hospital, however…
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27-year-old Fukazawa Misaki and 29-year-old Hazuki are sisters who are polar opposites in both lifestyle and personality. Although they would hurt each other's feelings, they would also make up for each other’s deficiencies. The beautiful Misaki is the typical younger sister who is good at putting on the little girl act. She did not fare well academically but knows how to swim with the tide. After graduating from high school, she left home and went missing. But one day, she suddenly moves into Hazuki's apartment and behaves with wild abandon. However, Misaki has a secret which she keeps to herself... Hazuki works at a ward office and has set her sights on an early marriage to her boyfriend who works in the same office. She is the well-organised, fastidious chairperson type, but is a wee bit socially awkward. Hazuki feels that Misaki snatched all their mother's love in childhood. What will happen now that Misaki has moved in with her? Hazuki actually has a secret which she cannot tell Misaki too. As these two sisters clash while living under the same roof, their values start to change little by little.
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Meisuke Nueno (Ryuhei Maruyama) is the homeroom teacher of a 2nd grade 3 class in high school. He is referred to as Nube. He sometimes carries himself as an idiot, but he does care about his students a lot. He also has a hidden side. Meisuke Nueno has a demon's hand. He solves monstrous case and fights desperately to save students from monsters
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Hara Heisuke (Nishikido Ryo) works as a teacher at an all boys high school in Shizuoka Prefecture. 14 years ago he had an unfortunate accident which made his life go crazy. He has since become obsessed with his hometown and the school where he graduated from. Due to declining enrollment at the all boys high school where Hara Heisuke works, the school plans to merge with an all girls high school next year. Prior to the merger of the schools, a culture festival is held for the students from the two schools. Hara struggles to make the culture festival a success.
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Freelancer surgeon Michiko (Ryoko Yonekura) visits an island. Due to an accident by a luxury liner, some of its passengers are injured. Among the injured passengers, Michiko finds Ryonosuke (Shiro Ito). Ryonosuke is an ex-hospital director with whom Michiko has worked for in the past. Michiko treats Ryonosuke's wound. Later, Ryonosuke is hospitalized at the National Center for Advanced Medical Care. He has suffered from a cardiac tumor and hepatocellular carcinoma. At the conference for Ryonosuke’s upcoming surgery, two factions of the National Center for Advanced Medical Care have an intense argument over his surgery. Michiko suddenly appears at the warlike conference and tells them that Ryonosuke is her patient.